Description

1,4-Dibromobicyclo[2.2.2]octane is a high-purity, specialized brominated bicyclic alkane building block. This compound is valued for its rigid, three-dimensional structure, making it an essential intermediate in advanced organic synthesis and materials science research. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for creating conformationally restricted analogs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides that require specific steric properties.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing bulky, electron-donating phosphine or N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Polymer & Material Science: Incorporated as a cross-linking agent or monomer to create polymers with enhanced thermal stability and rigid backbone structures.
• Organic Electronic Materials: Investigated as a building block for hole-transport or host materials in OLEDs and other electronic devices due to its non-planar geometry.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and C-H functionalization.

Basic Information

Product Name	1,4-Dibromobicyclo[2.2.2]octane
CAS No.	10364-04-2
Molecular Formula	C8H12Br2
Molecular Weight	275.99 g/mol
Synonyms	1,4-Dibromobicyclo[2.2.2]octane; Bicyclo[2.2.2]octane, 1,4-dibromo-; 1,4-Dibromoadamantane (common misnomer); 1,4-Dibromotricyclo[2.2.2.0]octane; DBCO-Br2; NSC 163063; 1,4-DBBO; p-Dibromobicyclooctane
EINECS	Contact for details

Quality Control

Our 1,4-Dibromobicyclo[2.2.2]octane is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, impurities, and physical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.