Description

p-Xylylenebis(Triphenylphosphonium Bromide) is a high-purity, versatile bisphosphonium salt widely utilized as a key reagent in organic synthesis. Its primary value lies in its role as a precursor for generating reactive p-xylylene intermediates via the Ramberg–Bäcklund reaction and as a potent phase-transfer catalyst. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for constructing complex molecular frameworks and facilitating challenging chemical transformations. Its consistent quality ensures reliable performance in critical synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for constructing complex drug molecules, especially those containing p-xylylene or stilbene cores.
• Ramberg–Bäcklund Reaction Reagent: Serves as the definitive precursor for generating reactive p-xylylene intermediates used to form alkenes from sulfones.
• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, enhancing reaction rates and yields in alkylation and other key industrial processes.
• Polymer & Material Science: Employed in the synthesis of specialty polymers, dendrimers, and advanced functional materials requiring precise molecular architecture.
• Agrochemical Research: Used in the development and synthesis of novel active ingredients for crop protection agents.
• Ligand & Complex Precursor: Acts as a precursor for phosphine ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	p-Xylylenebis(Triphenylphosphonium Bromide)
CAS No.	10273-74-2
Molecular Formula	C44H38Br2P2
Molecular Weight	772.51 g/mol
Synonyms	1,4-Bis(triphenylphosphoniomethyl)benzene dibromide; α,α'-Bis(triphenylphosphonio)-p-xylene dibromide; p-Xylylene bis(triphenylphosphonium) dibromide; p-Bis(triphenylphosphoniomethyl)benzene dibromide; NSC 169049; p-Xylylenebis(triphenylphosphonium) Bromide; p-Xylylene-α,α'-bis(triphenylphosphonium bromide)
EINECS	Contact for details

Quality Control

Our p-Xylylenebis(Triphenylphosphonium Bromide) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored in a cool, dry place, ideally under an inert atmosphere such as nitrogen or argon for long-term stability. Recommended storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.