Description

Pyridine-4-D1 is a deuterated derivative of pyridine, specifically labeled at the 4-position, with the CAS number 10259-15-1. This stable isotope-labeled compound is essential for advanced analytical research, providing a non-radioactive tracer for mechanistic studies and quantitative analysis. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and analytical instrumentation industries for applications in NMR spectroscopy, mass spectrometry, and metabolic pathway investigation.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis to ensure accuracy in pharmaceutical and environmental testing.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated solvent or a probing agent in nuclear magnetic resonance studies due to its distinct spectral properties.
• Metabolic Pathway Tracing: Acts as a stable isotopic tracer in drug metabolism and pharmacokinetics (DMPK) studies to track biochemical pathways.
• Pharmaceutical Intermediate: Employed in the synthesis of deuterated active pharmaceutical ingredients (APIs) for improved metabolic stability and patent life-cycle management.
• Agrochemical Research: Used in the development and analysis of novel deuterated pesticides and herbicides.
• Chemical Reaction Mechanism Studies: Aids in elucidating reaction mechanisms in organic and organometallic chemistry through kinetic isotope effect (KIE) studies.

Basic Information

Product Name	Pyridine-4-D1
CAS No.	10259-15-1
Molecular Formula	C5H4DN
Molecular Weight	80.11 g/mol
Synonyms	4-Deuteropyridine; Pyridine-d1 (4-position); [4-2H]Pyridine; Deuteriopyridine; Pyridine-4-d; 4-D-Pyridine; 4-Deutero-pyridine; Pyridine-4-2H
EINECS	Contact for details

Quality Control

Every batch of Pyridine-4-D1 is produced and analyzed under strict quality protocols to ensure high isotopic and chemical purity suitable for sensitive analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and solvent residues are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.