Description

(12Bs)-1,2,3,4,6,7,12,12Bβ-Octahydroindolo[2,3-A]Quinolizine is a complex, polycyclic indole alkaloid derivative that serves as a critical advanced intermediate in organic synthesis. This compound is valued for its intricate fused-ring structure, which provides a versatile scaffold for the development of novel pharmacologically active molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of complex heterocycles, alkaloid analogs, and potential new chemical entities for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex indole-based alkaloids and potential therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of new bioactive molecules targeting neurological and other disorders.
• Organic Synthesis Reference Standard: Serves as a high-purity reference material for analytical method development and verification in research laboratories.
• Asymmetric Synthesis: Utilized in the development of chiral catalysts or ligands due to its complex, three-dimensional structure.
• Natural Product Analog Synthesis: Employed in the semi-synthesis or total synthesis of analogs of naturally occurring indoloquinolizidine alkaloids.

Basic Information

Product Name	(12Bs)-1,2,3,4,6,7,12,12Bβ-Octahydroindolo[2,3-A]Quinolizine
CAS No.	10252-12-7
Molecular Formula	C₁₆H₂₀N₂
Molecular Weight	240.35 g/mol
Synonyms	(12bS)-1,2,3,4,6,7,12,12b-Octahydroindolo[2,3-a]quinolizine; (S)-1,2,3,4,6,7,12,12b-Octahydroindolo[2,3-a]quinolizine; (S)-Octahydroindolo[2,3-a]quinolizine; (S)-OHIQ; Indolo[2,3-a]quinolizine, 1,2,3,4,6,7,12,12b-octahydro-, (12bS)-; Tetrahydroalstonine (partial structure analog); Alkaloid C-16H20N2; 12bS-Octahydroindolo[2,3-a]quinolizine
EINECS	Contact for details

Quality Control

Our (12Bs)-1,2,3,4,6,7,12,12Bβ-Octahydroindolo[2,3-A]Quinolizine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including chiral purity verification. A detailed Certificate of Analysis (COA) providing identity, purity (HPLC), and impurity profile is supplied with every shipment to support your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.