Description

(1R,9Ar)-Octahydro-2H-Quinolizin-1-Ylmethanol(Saltdata: Free) CAS NO 10248-30-3 is a high-purity chiral intermediate of significant value in advanced organic synthesis. Its rigid, fused bicyclic structure makes it a critical building block for the development of complex pharmaceutical molecules, particularly those targeting neurological and cardiovascular pathways. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries who require precise stereochemistry and reliable quality for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for alkaloid-derived therapeutics.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for developing novel chiral ligands and catalysts used in enantioselective synthesis.
• Agrochemical Research: Used in the development of new crop protection agents and pesticides that require specific stereochemical configurations for optimal activity.
• Academic & R&D Laboratories: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and the creation of compound libraries.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural products and other high-value specialty chemicals.

Basic Information

Product Name	(1R,9Ar)-Octahydro-2H-Quinolizin-1-Ylmethanol(Saltdata: Free)
CAS No.	10248-30-3
Molecular Formula	C10H19NO
Molecular Weight	169.26 g/mol
Synonyms	(1R,9aR)-Octahydro-2H-quinolizin-1-ylmethanol; (1R,9aR)-Octahydro-1-quinolizinemethanol; (1R,9aR)-1-(Hydroxymethyl)octahydro-2H-quinolizine; (-)-Cuspareine; (1R,9aR)-1-Quinolizinemethanol, octahydro-; (1R,9aR)-1-Hydroxymethyloctahydroquinolizine; (1R,9aR)-Octahydro-1-quinolizinylmethanol
EINECS	Contact for details

Quality Control

Our (1R,9Ar)-Octahydro-2H-Quinolizin-1-Ylmethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.