Description

2-Bromo-4,5-Dihydro-3H-Naphtho[1,8-Bc]Thiophen-5-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its fused naphthothiophene structure. This compound is valued for its role as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Organic Synthesis Building Block: Utilized in research-scale and process chemistry for constructing complex polycyclic frameworks via cross-coupling reactions, substitutions, or further functionalization.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in the discovery of new therapeutic agents.
• Material Science Precursor: Potential use in the development of organic electronic materials or specialty dyes due to its conjugated naphthothiophene system.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-Bromo-4,5-Dihydro-3H-Naphtho[1,8-Bc]Thiophen-5-Ol
CAS No.	10245-75-7
Molecular Formula	C₁₄H₁₁BrOS
Molecular Weight	307.20 g/mol
Synonyms	2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophen-5-ol; 2-Bromonaphtho[1,8-bc]thiophen-5-ol; 5-Hydroxy-2-bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene; 10245-75-7; Naphtho[1,8-bc]thiophen-5-ol, 2-bromo-4,5-dihydro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,5-Dihydro-3H-Naphtho[1,8-Bc]Thiophen-5-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.