Description

3-(1H-Indol-3-Yl)Pyrrolidine-2,5-Dione is a heterocyclic organic compound featuring a pyrrolidine-2,5-dione (succinimide) core substituted with an indole moiety. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules, particularly those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology drug candidates.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry to create libraries of compounds for biological activity testing.
• Biochemical Research: Serves as a precursor or reference standard in studies investigating enzyme inhibition or receptor-ligand interactions.
• Organic Synthesis: Employed in academic and industrial research for constructing complex heterocyclic frameworks due to its reactive imide and indole functional groups.

Basic Information

Product Name	3-(1H-Indol-3-Yl)Pyrrolidine-2,5-Dione
CAS No.	10185-29-2
Molecular Formula	C12H10N2O2
Molecular Weight	214.22 g/mol
Synonyms	3-(1H-Indol-3-yl)pyrrolidine-2,5-dione; 3-Indol-3-yl-pyrrolidine-2,5-dione; 3-(3-Indolyl)succinimide; 1H-Indole-3-succinimide; 3-(1H-Indol-3-yl)-2,5-pyrrolidinedione; Succinimide, 3-(3-indolyl)-; 3-Indolylsuccinimide
EINECS	Contact for details

Quality Control

Our production of 3-(1H-Indol-3-Yl)Pyrrolidine-2,5-Dione adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.