Description

2-Amino-1-(3,4-Difluorophenyl)Ethanol is a high-value chiral amino alcohol intermediate featuring a difluorinated aromatic ring. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical active ingredients, particularly those targeting the central nervous system. Pharmaceutical R&D and fine chemical manufacturers need this material for developing new drug candidates, where its structural motifs are leveraged to enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel antidepressants, antipsychotics, and other neuroactive compounds.
• Agrochemical Research: Used in developing advanced crop protection agents and herbicides due to its fluorinated aromatic structure.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis for producing enantiomerically pure compounds.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical entities.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	2-Amino-1-(3,4-Difluorophenyl)Ethanol
CAS No.	10145-04-7
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	1-(3,4-Difluorophenyl)-2-aminoethanol; 2-Amino-1-(3,4-difluorophenyl)ethan-1-ol; 3,4-Difluoro-β-aminoethylbenzene; (R/S)-2-Amino-1-(3,4-difluorophenyl)ethanol; 2-Amino-1-(3,4-difluorophenyl)ethyl alcohol; α-Amino-3,4-difluorobenzeneethanol; β-Amino-3,4-difluorophenethyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(3,4-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.