Description

3-Isoquinolinecarboxylic Acid, 1,2-Dihydro-4-Hydroxy-7-Nitro-1-Oxo-, Methyl Ester is a high-purity, synthetically valuable heterocyclic building block characterized by its nitro and ester functional groups. This compound is critical for advanced organic synthesis, serving as a key intermediate in the development of complex molecules with potential biological activity. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and the synthesis of novel fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of new active ingredients for crop protection products.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex heterocyclic compounds for various high-value industrial applications.
• Academic & R&D: Utilized in university and institutional laboratories for methodological development and exploratory organic synthesis.

Basic Information

Product Name	3-Isoquinolinecarboxylic Acid, 1,2-Dihydro-4-Hydroxy-7-Nitro-1-Oxo-, Methyl Ester
CAS No.	10133-83-2
Molecular Formula	C11H8N2O6
Molecular Weight	264.19 g/mol
Synonyms	Methyl 1,2-dihydro-4-hydroxy-7-nitro-1-oxo-3-isoquinolinecarboxylate; 1,2-Dihydro-4-hydroxy-7-nitro-1-oxo-3-isoquinolinecarboxylic acid methyl ester; 3-Carbomethoxy-1,2-dihydro-4-hydroxy-7-nitro-1-oxoisoquinoline; 4-Hydroxy-7-nitro-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxylic Acid, 1,2-Dihydro-4-Hydroxy-7-Nitro-1-Oxo-, Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.