Description

(R)-A-Hydroxy-2-Thiopheneacetonitrile is a high-value chiral building block and pharmaceutical intermediate. This compound matters for its role in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of advanced, optically active pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel catalytic systems for stereoselective reactions.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry within university and corporate laboratories.

Basic Information

Product Name	(R)-A-Hydroxy-2-Thiopheneacetonitrile
CAS No.	10017-06-8
Molecular Formula	C7H5NOS
Molecular Weight	151.18 g/mol
Synonyms	(R)-2-Hydroxy-2-(2-thienyl)acetonitrile; (R)-α-Hydroxy-2-thiopheneacetonitrile; (R)-Hydroxy(thiophen-2-yl)acetonitrile; (2R)-2-Hydroxy-2-(thiophen-2-yl)acetonitrile; (R)-Thiophene-2-glycolic acid nitrile; (R)-2-Thienylglycolonitrile; (R)-TGA; (R)-TAN
EINECS	Contact for details

Quality Control

Our (R)-A-Hydroxy-2-Thiopheneacetonitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.