Description

1H-Indole-2-Propanoic Acid, A-Amino- is a high-purity, non-proteinogenic amino acid derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique indole-based structure provides a versatile scaffold for constructing complex molecules with specific biological activity. This compound is essential for research and development in the pharmaceutical industry, particularly for medicinal chemists and process development scientists working on novel therapeutic agents and fine chemical production.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurological and metabolic disorder research.
• Peptidomimetics & Drug Design: Used to incorporate unnatural amino acid motifs into peptide analogs to enhance stability, bioavailability, and receptor selectivity.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme inhibition assays.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Agrochemical Development: Potential intermediate for creating novel plant growth regulators or specialty agrochemicals with specific modes of action.
• Material Science: Can be utilized in the synthesis of specialty polymers or organic electronic materials that require functionalized heterocyclic components.

Basic Information

Product Name	1H-Indole-2-Propanoic Acid, A-Amino-
CAS No.	1954-56-9
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	2-Amino-3-(1H-indol-2-yl)propanoic acid; α-Amino-1H-indole-2-propanoic acid; 3-(1H-Indol-2-yl)-L-alanine; (S)-2-Amino-3-(1H-indol-2-yl)propanoic acid; Tryptophan isomer; 2-(2-Aminopropanoic acid)-1H-indole; β-(2-Indolyl)-L-alanine; 1954-56-9
EINECS	217-809-5

Quality Control

Our 1H-Indole-2-Propanoic Acid, A-Amino- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.