Description

(2R,3S)-1,4-Dibromo-2,3-Butanediol is a high-purity chiral building block and versatile synthetic intermediate of significant commercial interest. Its value lies in its stereochemically defined structure, which is crucial for synthesizing enantiomerically pure compounds in advanced research and development. This product is essential for pharmaceutical chemists, agrochemical researchers, and specialty chemical manufacturers requiring precise molecular architecture for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where specific stereochemistry is critical for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Acts as a bifunctional monomer or cross-linking agent for creating specialty polymers with specific properties.
• Fine Chemical Production: Employed in multistep syntheses of complex natural products, flavors, and fragrances.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(2R,3S)-1,4-Dibromo-2,3-Butanediol
CAS No.	1947-59-7
Molecular Formula	C4H8Br2O2
Molecular Weight	247.91 g/mol
Synonyms	(2R,3S)-1,4-Dibromobutane-2,3-diol; (2R,3S)-1,4-Dibromo-2,3-dihydroxybutane; erythro-1,4-Dibromo-2,3-butanediol; (R*,S*)-(±)-1,4-Dibromo-2,3-butanediol; 1,4-Dibromo-2,3-butanediol (erythro); DL-erythro-1,4-Dibromo-2,3-butanediol; 2,3-Butanediol, 1,4-dibromo-, erythro-
EINECS	217-763-5

Quality Control

Our (2R,3S)-1,4-Dibromo-2,3-Butanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.