Description

4-Chloro-3,5-Dinitrobenzonitrile is a versatile aromatic nitrile derivative characterized by its chloro and nitro substituents, making it a valuable synthetic intermediate. This compound is crucial for its role in facilitating complex organic transformations, particularly in the synthesis of advanced heterocyclic systems and functional materials. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing benzimidazole or quinazoline cores.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where its nitro and cyano groups enable further functionalization.
• Dye and Pigment Precursor: Acts as a starting material for the development of specialized azo dyes and high-performance pigments due to its electron-withdrawing substituents.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers where its planar, substituted benzene ring contributes to desired electronic properties.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures common in advanced materials.
• Nucleophilic Aromatic Substitution: The activated chloro group between two nitro groups makes it an excellent candidate for SNAr reactions to introduce amines, alkoxides, or other nucleophiles.

Basic Information

Product Name	4-Chloro-3,5-Dinitrobenzonitrile
CAS No.	1930-72-9
Molecular Formula	C7H2ClN3O4
Molecular Weight	227.56 g/mol
Synonyms	3,5-Dinitro-4-chlorobenzonitrile; 4-Chloro-3,5-dinitrobenzenecarbonitrile; Benzonitrile, 4-chloro-3,5-dinitro-; 1-Chloro-2,6-dicyano-3,5-dinitrobenzene (alternative numbering); 4-Chloro-3,5-dinitro-benzonitril; NSC 403116
EINECS	217-707-5

Quality Control

Our 4-Chloro-3,5-Dinitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound should be stored separately from strong bases, reducing agents, and reactive metals.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.