Description

3,4-(Methylenedioxy)Phenylacetonitrile is a versatile aromatic nitrile building block characterized by its methylenedioxy functional group. This compound is a critical intermediate in organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzodioxole or piperonyl structural motifs.
• Agrochemical Synthesis: Used in the production of insecticides, herbicides, and fungicides, where the methylenedioxy group can enhance biological activity.
• Fine Chemical Manufacturing: Serves as a building block for dyes, pigments, and other performance chemicals requiring specific aromatic frameworks.
• Research & Development: Employed in academic and industrial R&D for method development and the creation of novel chemical entities for screening.
• Flavor & Fragrance Industry: Potential intermediate in the synthesis of certain aroma chemicals, though specific applications require verification.

Basic Information

Product Name	3,4-(Methylenedioxy)Phenylacetonitrile
CAS No.	4439-02-5
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	Piperonylacetonitrile; 1,3-Benzodioxole-5-acetonitrile; 3,4-Methylenedioxyphenylacetonitrile; (Benzo[d][1,3]dioxol-5-yl)acetonitrile; 5-Cyanomethyl-1,3-benzodioxole; MDAN; Contact for details on additional trade names.
EINECS	224-647-6

Quality Control

Our production of 3,4-(Methylenedioxy)Phenylacetonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and IR/NMR for structural confirmation. We provide detailed Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your specifications. Our quality system is designed to support applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.