Description

4-Aminophenylacetonitrile is a versatile aromatic nitrile building block featuring both an amine and a nitrile functional group. This compound is of significant commercial importance for its role as a key intermediate in the synthesis of complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) drugs and other therapeutic agents.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides, leveraging its aromatic amine-nitrile structure.
• Dye and Pigment Manufacturing: Used in the production of specialized dyes, pigments, and colorants due to its reactive amine group which can be diazotized and coupled.
• Polymer and Resin Modifier: Acts as a monomer or cross-linking agent in the production of specialty polymers, resins, and high-performance materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing heterocyclic compounds, such as indoles and quinolines, via cyano-group transformations.
• Chemical Research: Utilized as a standard or starting material in methodological studies and catalysis research for C-N and C-C bond formation reactions.

Basic Information

Product Name	4-Aminophenylacetonitrile
CAS No.	3544-25-0
Molecular Formula	C8H8N2
Molecular Weight	132.16 g/mol
Synonyms	p-Aminophenylacetonitrile; (4-Aminophenyl)acetonitrile; 4-Cyanobenzylamine; 2-(4-Aminophenyl)acetonitrile; 4-Aminobenzyl cyanide; USAF EK-4965; NSC 408926; p-Cyanobenzylamine
EINECS	222-593-8

Quality Control

Our 4-Aminophenylacetonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.