Description

4-Chloro-3-Hydroxy Butyronitrile is a versatile bifunctional organic intermediate containing both a reactive chloro and a hydroxy group on a nitrile backbone. This compound matters for its role as a key building block in the synthesis of complex pharmaceutical molecules and fine chemicals. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical producers for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of statin drugs (cholesterol-lowering agents) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its reactive sites for constructing heterocyclic structures.
• Fine Chemical Building Block: Serves in the manufacture of specialty chemicals, including polymers, dyes, and complex organic ligands.
• Research & Development: Employed in academic and industrial labs for exploring new synthetic pathways and developing novel chemical entities.
• Chiral Synthesis: Utilized as a starting material for the preparation of chiral compounds due to its potential for asymmetric transformations.

Basic Information

Product Name	4-Chloro-3-Hydroxy Butyronitrile
CAS No.	105-33-9
Molecular Formula	C4H6ClNO
Molecular Weight	119.55 g/mol
Synonyms	3-Hydroxy-4-chlorobutyronitrile; 4-Chloro-3-hydroxybutyronitrile; γ-Chloro-β-hydroxybutyronitrile; 4-Chloro-3-hydroxybutanenitrile; (RS)-4-Chloro-3-hydroxybutyronitrile; 105-33-9; Butyronitrile, 4-chloro-3-hydroxy-; NSC 403697
EINECS	203-287-6

Quality Control

Our 4-Chloro-3-Hydroxy Butyronitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) are provided with every shipment, and we support compliance with REACH and other major global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere for long-term storage to maintain purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.