Description

2-Thiopheneacetic Acid is a versatile heterocyclic building block and organic synthetic intermediate of significant commercial importance. Its unique structure, featuring a thiophene ring linked to an acetic acid moiety, makes it a critical precursor for the development of advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with tailored properties.

Application

• Pharmaceutical Intermediates: A key starting material in the synthesis of various drug candidates, particularly non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging the thiophene ring's bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Polymer and Material Science: Employed in the synthesis of functionalized monomers for conductive polymers, organic semiconductors, and advanced polymeric materials.
• Organic Synthesis Building Block: Utilized in various name reactions and coupling processes to introduce the 2-thienylmethyl fragment into more complex molecular architectures.
• Research and Development: A valuable reagent for medicinal chemistry and chemical biology research in academic and industrial R&D laboratories.

Basic Information

Product Name	2-Thiopheneacetic Acid
CAS No.	1918-77-0
Molecular Formula	C6H6O2S
Molecular Weight	142.18 g/mol
Synonyms	2-Thienylacetic Acid; (2-Thienyl)acetic Acid; Thiophen-2-ylacetic Acid; 2-Thiophene Acetic Acid; α-Thiopheneacetic Acid; TAA; 2-Carboxymethylthiophene; 2-Thienylethanoic Acid
EINECS	217-645-8

Quality Control

Our 2-Thiopheneacetic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	76 - 79 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.