Description

2,2'-Dithiodiethanol is a versatile sulfur-containing organic compound with a disulfide linkage, serving as a critical building block and intermediate in advanced chemical synthesis. Its bifunctional structure, featuring both hydroxyl and disulfide groups, makes it a valuable precursor for creating cross-linking agents, polymer modifiers, and specialty additives. This product is essential for R&D laboratories and industrial manufacturers in the pharmaceutical, polymer, and personal care sectors seeking to develop novel materials with specific properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring a cleavable disulfide bond for targeted drug delivery.
• Polymer & Resin Modification: Acts as a cross-linking agent or chain extender in the production of polyurethanes, epoxy resins, and other specialty polymers to enhance mechanical strength and thermal stability.
• Hair Care & Cosmetic Formulations: Employed as a key ingredient in permanent wave solutions and hair straightening products, where the disulfide bond is crucial for restructuring keratin.
• Bioconjugation & Protein Chemistry: Serves as a linker molecule for attaching peptides, proteins, or fluorescent tags in biochemical research and diagnostic assay development.
• Lubricant & Fuel Additive: Functions as an anti-wear agent and extreme pressure additive in synthetic lubricants and industrial fluids.
• Chemical Synthesis Reagent: A versatile reagent for organic synthesis, used in reactions to introduce disulfide bridges or as a protecting group for diols.

Basic Information

Product Name	2,2'-Dithiodiethanol
CAS No.	1892-29-1
Molecular Formula	C4H10O2S2
Molecular Weight	154.25 g/mol
Synonyms	Bis(2-hydroxyethyl) disulfide; 2-Hydroxyethyl disulfide; Dithiodiglycol; Di(2-hydroxyethyl) disulfide; 2,2'-Dihydroxyethyl disulfide; Thiodiglycol disulfide; Ethanol, 2,2'-dithiobis-; β,β'-Dihydroxydiethyl disulfide; Dithiobis(ethanol)
EINECS	217-568-1

Quality Control

Our 2,2'-Dithiodiethanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, identification, and impurity profiling, to ensure it meets the high standards required for industrial and research applications. A Certificate of Analysis (COA) detailing purity, physical properties, and test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The product may be hygroscopic; ensure containers are sealed tightly after use to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.520 - 1.525
Density (20°C)	1.23 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.