Description

Salicylic Acid-Carboxy-14C is a carbon-14 radiolabeled derivative of salicylic acid, specifically labeled at the carboxylic acid carbon position. This compound is a critical tool for advanced metabolic and pharmacokinetic studies, enabling precise tracking of the parent molecule and its metabolites in biological and environmental systems. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and life science sectors requiring high-specific-activity tracers for autoradiography, LC-MS, and ADME studies.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a radiotracer to investigate the absorption, distribution, metabolism, and excretion (ADME) of salicylate-based pharmaceuticals.
• Environmental Fate Studies: Tracks the degradation, transformation, and binding of salicylic acid and related compounds in soil and water systems.
• Biosynthetic Pathway Analysis: Elucidates the metabolic pathways in plants and microorganisms involving salicylic acid, a key plant hormone and defense signaling molecule.
• Analytical Method Development: Serves as an internal standard or recovery tracer in the development and validation of sensitive LC-MS/MS and HPLC-radioactivity detection methods.
• Receptor Binding Assays: Facilitates the study of protein binding and receptor interactions for salicylate-based compounds.
• Quality Control for Radiolabeled Compounds: Used as a reference standard in the synthesis and purity verification of other carbon-14 labeled materials.

Basic Information

Product Name	Salicylic Acid-Carboxy-14C
CAS No.	1882-49-1
Molecular Formula	C7H6O3 (with 14C at C1)
Molecular Weight	~138.12 g/mol (exact mass depends on specific activity)
Synonyms	2-Hydroxy[1-14C]benzoic acid; [Carboxy-14C]-Salicylic Acid; 14C-Salicylic Acid; Benzoic acid, 2-hydroxy-, (carboxy-14C)-; Radiolabeled Salicylic Acid; SA-14C; Tracer SA
EINECS	Contact for details

Quality Control

Every batch of Salicylic Acid-Carboxy-14C is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to ensure product integrity for your critical research. Key quality attributes include radiochemical purity (typically >98% by HPLC), specific activity, and chemical purity. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting the results.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, secure area for radioactive materials. Ensure storage conditions comply with all local and national regulations for handling radiolabeled compounds.

Specification

Item	Specification
Appearance	White to Off-White Solid
Identification (IR/HPLC)	Conforms to Reference Standard
Assay (Radiochemical Purity)	≥ 98%
Specific Activity	50-60 mCi/mmol (Customizable)
Solvent (if supplied in solution)	Ethanol or other specified solvent
Radioactivity Concentration	As per customer requirement

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.