Description

3-Methyleneoxindole is a versatile heterocyclic building block and a key intermediate in organic synthesis. Its unique exocyclic methylene group adjacent to the oxindole core makes it a valuable precursor for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients. Its reactivity profile enables applications in material science and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of bioactive molecules, including kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides.
• Organic Synthesis Reagent: Serves as a Michael acceptor or a dienophile in cycloaddition reactions for constructing complex heterocycles.
• Material Science Research: Investigated as a monomer or precursor for functional polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways.
• Academic & R&D: A crucial compound for methodological development and discovery chemistry in university and industrial laboratories.

Basic Information

Product Name	3-Methyleneoxindole
CAS No.	1861-29-6
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	3-Methylene-1,3-dihydro-2H-indol-2-one; 3-Methylene-2-indolinone; 2-Indolinone, 3-methylene-; 3-Methylenoxindole; 3-Methyleneindolin-2-one; Isatin methylene; 1,3-Dihydro-3-methylene-2H-indol-2-one
EINECS	217-458-8

Quality Control

Our 3-Methyleneoxindole is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Off-white to light yellow powder/crystals
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.