Description

2-Bromothiophene-3-Carbaldehyde is a versatile and high-purity brominated heterocyclic building block essential for advanced organic synthesis. Its reactive aldehyde and bromine functional groups make it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new generation herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science & Organic Electronics: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and sensors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Research & Development: A fundamental reagent for method development in cross-coupling reactions (e.g., Suzuki, Stille) and for exploring new heterocyclic chemistry.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene ring enhances color fastness and electronic properties.

Basic Information

Product Name	2-Bromothiophene-3-Carbaldehyde
CAS No.	1860-99-7
Molecular Formula	C5H3BrOS
Molecular Weight	191.05 g/mol
Synonyms	3-Bromo-2-thiophenecarboxaldehyde; 3-Bromothiophene-2-carbaldehyde; 2-Bromo-3-formylthiophene; 3-Bromo-2-formylthiophene; 2-Bromothiophene-3-carboxaldehyde; 3-Bromothiophene-2-carboxaldehyde; 2-Bromo-3-thiophenecarboxaldehyde
EINECS	217-468-4

Quality Control

Our 2-Bromothiophene-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	48 - 52 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.