Description

4-Nitrothiophenol is a versatile aromatic thiol derivative characterized by its nitro-substituted benzene ring. This compound is a valuable chemical intermediate and ligand precursor in advanced organic synthesis and materials science. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring thiol or disulfide linkages.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and fungicides where the nitro-thiophenol moiety imparts specific biological activity.
• Ligand for Metal Complexes: Acts as a precursor for creating thiolate ligands in coordination chemistry and catalysis, useful in material synthesis and industrial catalytic processes.
• Polymer Modification: Employed in the functionalization of polymers and surfaces to introduce nitroarylthiol groups, altering material properties like adhesion or conductivity.
• Research & Development: A crucial reagent in academic and industrial R&D for exploring new organic reactions, heterocyclic chemistry, and molecular electronics.
• Surface Chemistry & Self-Assembled Monolayers (SAMs): Used to create functionalized surfaces on gold and other metals for sensor development and nanotechnology applications.

Basic Information

Product Name	4-Nitrothiophenol
CAS No.	1849-36-1
Molecular Formula	C6H5NO2S
Molecular Weight	155.17 g/mol
Synonyms	p-Nitrothiophenol; 4-Nitrobenzenethiol; 4-Nitrothiophenol; p-Nitrobenzenethiol; 4-Nitro-1-benzenethiol; 1-Mercapto-4-nitrobenzene; 4-Nitro-phenyl mercaptan; (4-Nitrophenyl)thiol
EINECS	217-428-7

Quality Control

Our 4-Nitrothiophenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	76 - 80 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.