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N,N'-Bis(Trimethylsilyl)Ethylenediamine CAS NO 1821-99-4


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CAS No.:1821-99-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N,N'-Bis(Trimethylsilyl)Ethylenediamine is a specialized organosilicon compound that serves as a versatile silylating agent and protecting group reagent. Its value lies in its ability to efficiently introduce trimethylsilyl groups onto amines and other nucleophiles, facilitating synthesis and purification processes in advanced chemical manufacturing. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries, where precise molecular modification is critical.

Application

  • Pharmaceutical Intermediate Synthesis: Used as a protecting group for primary and secondary amines during multi-step synthesis of active pharmaceutical ingredients (APIs).
  • Agrochemical Production: Employed in the manufacture of advanced pesticides and herbicides where silylation improves process yields or compound stability.
  • Silicon-Based Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialized silicones and silicon-containing polymers.
  • Derivatization Agent for Analysis: Utilized in Gas Chromatography (GC) and Mass Spectrometry (MS) to enhance the volatility and detectability of polar compounds like amino acids and sugars.
  • Catalyst and Ligand Preparation: Serves as a precursor for creating nitrogen-containing ligands used in homogeneous catalysis.
  • Surface Modification: Applied in material science to functionalize surfaces with silyl groups, altering wettability and adhesion properties.

Basic Information

Product Name N,N'-Bis(Trimethylsilyl)Ethylenediamine
CAS No. 1821-99-4
Molecular Formula C8H24N2Si2
Molecular Weight 204.46 g/mol
Synonyms 1,2-Bis(trimethylsilylamino)ethane; N,N'-Bis(trimethylsilyl)-1,2-ethanediamine; Ethylenediamine, N,N'-bis(trimethylsilyl)-; BTMSE; TMS-EDA; Bis(trimethylsilyl)ethylenediamine; 1,2-Ethanediamine, N,N-bis(trimethylsilyl)-
EINECS 217-350-6

Quality Control

Our N,N'-Bis(Trimethylsilyl)Ethylenediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including Gas Chromatography (GC) and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) and highly volatile nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Density (at 20°C) 0.82 - 0.86 g/mL
Refractive Index (n20D) 1.430 - 1.435

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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