Description

2-Amino-4-Methyl-5-Hydroxyethylthiazole is a versatile heterocyclic organic compound that serves as a key intermediate in the synthesis of more complex molecules. Its value lies in its functional thiazole ring and reactive amino and hydroxyethyl groups, making it a crucial building block for pharmaceutical and agrochemical research. This compound is primarily needed by manufacturers and R&D facilities in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing thiazole moieties.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and insecticides, leveraging its bioactive heterocyclic structure.
• Vitamin B1 (Thiamine) Analogues: Serves as a key building block in the research and synthesis of thiamine derivatives and related compounds.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other specialty chemicals requiring a functionalized thiazole core.
• Biochemical Research: Utilized as a reagent in life science research for studying enzyme interactions and developing biochemical probes.
• Material Science: Investigated as a monomer or additive in the development of novel polymers with specific electronic or optical properties.

Basic Information

Product Name	2-Amino-4-Methyl-5-Hydroxyethylthiazole
CAS No.	1820-94-6
Molecular Formula	C6H10N2OS
Molecular Weight	158.22 g/mol
Synonyms	5-(2-Hydroxyethyl)-4-methylthiazol-2-amine; 4-Methyl-5-(2-hydroxyethyl)thiazol-2-amine; 2-Amino-4-methyl-5-(2-hydroxyethyl)thiazole; 2-Amino-4-methyl-5-β-hydroxyethylthiazole; Thiamine intermediate; Vitamin B1 intermediate; AMHET; 2-Amino-4-methyl-5-(2'-hydroxyethyl)thiazole
EINECS	217-342-7

Quality Control

Our 2-Amino-4-Methyl-5-Hydroxyethylthiazole is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	140 - 144 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.