Description

2-tert-Butyl-1H-Indole (CAS NO 1805-65-8) is a specialized alkylated indole derivative that serves as a crucial synthetic intermediate and building block in advanced organic chemistry. Its unique sterically hindered structure provides distinct reactivity and stability, making it valuable for the development of novel compounds with specific functional properties. This high-purity intermediate is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its heterocyclic core.
• Material Science Research: Acts as a precursor or functional additive in the development of advanced organic electronic materials and specialty polymers.
• Fragrance & Flavor Chemistry: Serves as a starting material for synthesizing complex aroma chemicals due to the indole scaffold's relevance in musk and floral notes.
• Organic Synthesis & Catalysis: Employed as a ligand or a sterically demanding substrate in metal-catalyzed cross-coupling reactions and other transformative processes.
• Academic & R&D Laboratories: Essential reference standard and reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	2-tert-Butyl-1H-Indole
CAS No.	1805-65-8
Molecular Formula	C₁₂H₁₅N
Molecular Weight	173.25 g/mol
Synonyms	2-tert-Butylindole; 2-(1,1-Dimethylethyl)-1H-indole; 2-(tert-Butyl)indole; 2-t-Butylindole; 2-(2-Methyl-2-propanyl)-1H-indole; 1H-Indole, 2-(1,1-dimethylethyl)-; 2-tert-Butyl-1H-indole
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, GC for residual solvents, and spectroscopic identification (IR, NMR). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.