Description

2-(Trifluoromethyl)-5,6-Dimethyl-1H-Benzimidazole is a high-value, fluorinated benzimidazole derivative serving as a critical synthetic intermediate in advanced chemical manufacturing. Its core value lies in the unique reactivity imparted by the trifluoromethyl group, enabling the development of compounds with enhanced metabolic stability and lipophilicity. This product is essential for R&D and production teams in the pharmaceutical and agrochemical sectors, where it is used to construct novel active ingredients. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research programs.
• Agrochemical Synthesis: Used in the development of advanced fungicides, herbicides, and plant growth regulators, leveraging the bioactivity of the benzimidazole core.
• Material Science Precursor: Serves as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination chemistry and heterocyclic compound libraries.
• Ligand Synthesis for Catalysis: Utilized to prepare sophisticated N-donor ligands for transition metal catalysts used in fine chemical synthesis.

Basic Information

Product Name	2-(Trifluoromethyl)-5,6-Dimethyl-1H-Benzimidazole
CAS No.	1799-79-7
Molecular Formula	C10H9F3N2
Molecular Weight	214.19 g/mol
Synonyms	5,6-Dimethyl-2-(trifluoromethyl)-1H-benzimidazole; 2-(Trifluoromethyl)-5,6-dimethylbenzimidazole; 1H-Benzimidazole, 2-(trifluoromethyl)-5,6-dimethyl-; 5,6-Dimethyl-2-trifluoromethylbenzimidazole; 1799-79-7; α,α,α-Trifluoro-5,6-dimethyl-1H-benzimidazole-2-methane
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-5,6-Dimethyl-1H-Benzimidazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.