Description

Chloroacetic Acid-D3 CAS NO 1796-85-6 is a deuterated isotopologue of chloroacetic acid, where three hydrogen atoms are replaced by deuterium. This isotopic labeling is critical for applications requiring precise molecular tracking and reduced metabolic interference in research environments. It serves as an essential building block and analytical standard in advanced chemical synthesis and spectroscopic studies. Key users include pharmaceutical researchers, agrochemical developers, and academic institutions engaged in mechanistic studies and analytical method development.

Application

• Pharmaceutical Research & Development: Used as a deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification of chloroacetic acid and related compounds in biological matrices.
• Metabolic Pathway Tracing: Employed in pharmacokinetic and metabolic stability studies to track the fate of molecules without significant isotope effects, providing clearer insights into drug metabolism.
• Agrochemical Analysis: Functions as a high-purity reference standard for monitoring residues and degradation products of chlorinated herbicides in environmental and food safety testing.
• Organic Synthesis Intermediate: Acts as a labeled precursor in the synthesis of more complex deuterated compounds for use in NMR spectroscopy and other analytical techniques.
• Spectroscopic Calibration: Provides a sharp, well-defined signal for calibrating NMR and IR spectrometers due to the distinct properties of deuterium.
• Chemical Mechanism Elucidation: Utilized in reaction kinetics studies to investigate mechanisms involving proton transfer, where deuterium substitution provides valuable kinetic isotope effect (KIE) data.

Basic Information

Product Name	Chloroacetic Acid-D3
CAS No.	1796-85-6
Molecular Formula	C2D3ClO2
Molecular Weight	117.51 g/mol
Synonyms	Deuterochloroacetic Acid; Chloroacetic-d3 Acid; Monochloroacetic Acid-d3; 2-Chloroacetic Acid-d3; Deuterated Monochloroacetate; (D3)Chloroacetic Acid; α-Chloroacetic Acid-d3; MCA-d3
EINECS	Contact for details

Quality Control

Every batch of Chloroacetic Acid-D3 is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity suitable for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity by HPLC, and specific impurity profiles. Our quality systems support compliance with relevant standards for high-purity reference materials and advanced synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases, oxidizing agents, and reactive metals. Containers must be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Isotopic Purity (D-atom %)	≥ 98%
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.