Description

Methyltriphenylphosphonium Bromide is a versatile and widely used organophosphorus compound, essential as a key reagent in organic synthesis. Its primary value lies in its role as a highly effective ylide precursor for the Wittig reaction, enabling the synthesis of alkenes from carbonyl compounds with precise control over stereochemistry. This makes it a critical material for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to construct complex molecular architectures.

Application

• Wittig Olefination: The principal application is as a methylene transfer agent for converting aldehydes and ketones into terminal alkenes (methylene compounds).
• Pharmaceutical Intermediates: Synthesis of key chiral and non-chiral intermediates for active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Production of intermediates for herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the synthesis of organic ligands, liquid crystals, and polymers with specific olefinic functionalities.
• Fine Chemical Production: Manufacture of flavors, fragrances, and specialty chemicals requiring alkene building blocks.
• Academic & Industrial R&D: A staple reagent in research laboratories for method development and exploratory synthesis.

Basic Information

Product Name	Methyltriphenylphosphonium Bromide
CAS No.	1779-49-3
Molecular Formula	C19H18BrP
Molecular Weight	357.22 g/mol
Synonyms	Methyltriphenylphosphonium bromide; Triphenylmethylphosphonium bromide; (Methyl)triphenylphosphonium bromide; Phosphonium, methyltriphenyl-, bromide; MTPP bromide; Methyl(triphenyl)phosphonium bromide; NSC 146063; Methyltriphenylphosphonium bromide (MTPPB)
EINECS	217-218-6

Quality Control

Our Methyltriphenylphosphonium Bromide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay (by titration), identification (IR), and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Melting Point	230 - 235 °C
Loss on Drying	≤ 1.0 %
Solubility	Soluble in polar organic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.