Description

4-(Borane-Dimethylamino)Pyridine is a versatile and highly reactive organoboron reagent, specifically a borane-amine complex. This compound matters as a powerful and selective reducing agent, offering distinct advantages in complex synthetic transformations where milder or more controlled reactivity is required. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as asymmetric synthesis and the reduction of sensitive functional groups.

Application

• Asymmetric Reduction Catalyst: Employed as a chiral catalyst or catalyst precursor in the enantioselective reduction of ketones and imines.
• Pharmaceutical Intermediate Synthesis: Used in the critical reduction steps during the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Selective Reducing Agent: Provides controlled reduction of specific functional groups (e.g., aldehydes, ketones) in the presence of other sensitive moieties.
• Polymer Chemistry: Acts as an initiator or modifying agent in the synthesis of specialty polymers and advanced materials.
• Agrochemical Research: Utilized in the development and synthesis of novel herbicides, pesticides, and plant growth regulators.
• Academic & Process R&D: A valuable tool in methodological development and scale-up studies for novel synthetic routes.

Basic Information

Product Name	4-(Borane-Dimethylamino)Pyridine
CAS No.	1769-74-0
Molecular Formula	C7H13BN2
Molecular Weight	136.01 g/mol
Synonyms	4-(Dimethylaminopyridine) Borane Complex; DMAP-Borane; 4-DMAP-BH3; N,N-Dimethyl-4-aminopyridine Borane; Pyridine, 4-(dimethylamino)-, compd. with borane (1:1); 4-(Dimethylamino)pyridine-Borane; Borane - 4-(Dimethylamino)pyridine (1:1); 4-Dimethylaminopyridine Trihydroboron
EINECS	217-199-8

Quality Control

Our 4-(Borane-Dimethylamino)Pyridine is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and titration methods, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and tendency to be easily oxidized, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.