Description

Cyclohexane-D12 CAS NO 1735-17-7 is a fully deuterated isotopologue of cyclohexane, where all twelve hydrogen atoms are replaced by deuterium (²H). This high isotopic purity makes it an indispensable internal standard and solvent in advanced analytical chemistry, particularly for Nuclear Magnetic Resonance (NMR) spectroscopy. It is primarily used by research institutions, pharmaceutical developers, and chemical manufacturers requiring precise molecular structure elucidation and quantitative analysis without proton interference.

Application

• NMR Spectroscopy Solvent: A primary deuterated solvent for ¹H, ¹³C, and ²H NMR, providing a lock signal and a proton-free background.
• Internal Standard for Quantitative Analysis: Used in mass spectrometry (MS) and gas chromatography (GC) as a stable, non-interfering reference compound.
• Mechanistic Studies & Kinetic Isotope Effects (KIE): Essential for investigating reaction mechanisms where the C-D bond's slower cleavage rate compared to C-H provides critical insights.
• Pharmaceutical Research & Development: Employed in the synthesis and analysis of deuterated active pharmaceutical ingredients (APIs) and metabolic pathway tracing.
• Polymer Science Research: Used to study polymer dynamics, diffusion, and structure using NMR techniques.
• Material Science: Acts as a probing molecule in the study of porous materials, catalysts, and surface interactions.

Basic Information

Product Name	Cyclohexane-D12
CAS No.	1735-17-7
Molecular Formula	C6D12
Molecular Weight	96.22 g/mol
Synonyms	Perdeuterocyclohexane; Cyclohexane-d12; Deuterated Cyclohexane; Hexadeutero-cyclohexane; Cyclohexane (D12); Cyclohexane-D12 (99.5 atom % D); [²H12]Cyclohexane; Cyclohexane (Perdeutero)
EINECS	217-063-4

Quality Control

Every batch of Cyclohexane-D12 is produced and tested under stringent quality management protocols to ensure exceptional isotopic and chemical purity, critical for sensitive spectroscopic applications. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % D), chemical purity, and NMR spectral quality. Our commitment to traceability and batch-to-batch consistency supports reliable and reproducible research outcomes for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and ignition sources. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use to prevent evaporation and potential concentration of non-volatile residues. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to reference spectrum
Isotopic Purity (Atom % D)	≥ 99.5%
Chemical Purity (GC)	≥ 99.9%
Water Content (KF)	≤ 0.05%
NMR Solvent Suitability	Passes test (Residual ¹H signal)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.