Description

Tetrahydrofuran-D8 is a deuterated solvent of the highest analytical purity, essential for advanced spectroscopic and chemical research. Its core value lies in providing a non-interfering, isotopically labeled environment for precise nuclear magnetic resonance (NMR) spectroscopy, eliminating background signals from common solvents. This product is critically needed by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and academic sectors for structural elucidation, reaction mechanism studies, and metabolic research.

Application

• NMR Spectroscopy Solvent: Primary deuterated solvent for 1H, 13C, and other nuclei NMR analysis, providing a lock signal and minimizing solvent interference.
• Pharmaceutical Research: Used in the structural analysis and purity determination of active pharmaceutical ingredients (APIs) and complex organic molecules.
• Reaction Mechanism Studies: Serves as an inert, labeled medium for tracking deuterium incorporation and studying kinetic isotope effects.
• Polymer Science: Employed in the analysis of polymer structures and the study of polymerization kinetics where protonated solvents would obscure signals.
• Metabolomics & Biomolecular NMR: Essential for high-resolution NMR in biological samples, including protein-ligand interaction studies and metabolic profiling.
• Chemical Synthesis: Acts as a specialty solvent in synthesis requiring deuterium labeling or where reaction monitoring via NMR is conducted in situ.
• Analytical Reference Standard: Used as an internal standard or reference material in quantitative NMR (qNMR) and other advanced analytical techniques.

Basic Information

Product Name	Tetrahydrofuran-D8
CAS No.	1693-74-9
Molecular Formula	C4D8O
Molecular Weight	80.15 g/mol
Synonyms	Deuterated Tetrahydrofuran; THF-d8; Perdeuterotetrahydrofuran; [D8]-Tetrahydrofuran; Tetrahydrofuran-d8; Octadeuterooxolane; 2,2,3,3,4,4,5,5-Octadeuterotetrahydrofuran; NMR Solvent THF-d8
EINECS	Contact for details

Quality Control

Our Tetrahydrofuran-D8 is manufactured under stringent conditions to ensure exceptional isotopic and chemical purity, meeting the exacting requirements of modern analytical laboratories. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity by NMR, and residual solvent content. We adhere to rigorous internal quality standards to guarantee batch-to-batch consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. For long-term storage, consider sealing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Deuterium Content (D atom %)	≥ 99.5%
Chemical Purity (by 1H NMR)	≥ 99.9%
Water Content (Karl Fischer)	≤ 0.05%
Residual Protonated THF	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.