Description

Benzene-1,4-D2 is a deuterated aromatic compound where two hydrogen atoms at the 1 and 4 positions are replaced by deuterium (²H or D). This isotopic labeling makes it an essential tool in advanced spectroscopic studies and mechanistic research, providing a non-radioactive tracer with distinct NMR and mass spectral properties. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for reaction pathway elucidation, metabolic studies, and the synthesis of deuterated active pharmaceutical ingredients (APIs).

Application

• NMR Spectroscopy Solvent & Standard: Used as an internal standard or locking solvent in nuclear magnetic resonance (NMR) spectroscopy due to its distinct spectral signature.
• Mechanistic Reaction Studies: Acts as a deuterium tracer to investigate reaction mechanisms, kinetics, and isotopic effects in organic synthesis.
• Deuterated API Synthesis: Serves as a key building block in the production of deuterium-labeled pharmaceutical compounds, which can offer improved metabolic stability and pharmacokinetic profiles.
• Mass Spectrometry Reference: Employed as a reference standard in mass spectrometry for calibration and quantitative analysis.
• Advanced Materials Research: Used in the development of organic electronic materials and liquid crystals where isotopic substitution can modify physical properties.
• Metabolic Pathway Tracing: Utilized in biochemical and pharmacological research to trace the metabolic fate of compounds in biological systems.

Basic Information

Product Name	Benzene-1,4-D2
CAS No.	1684-46-4
Molecular Formula	C6H4D2
Molecular Weight	82.11 g/mol
Synonyms	1,4-Dideuteriobenzene; p-Dideuterobenzene; Benzene-d2 (1,4); [1,4-²H₂]Benzene; 1,4-Dideuterobenzol; p-Benzene-d2; Deuteriobenzene (1,4-d2); Benzene-1,4-dideutero
EINECS	Contact for details

Quality Control

Our Benzene-1,4-D2 is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analysis to ensure high isotopic purity and chemical integrity. Key parameters, including isotopic enrichment (D atom %), chemical purity (by GC), and identity confirmation (by NMR and IR), are verified. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and ignition points. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Isotopic Purity (D atom %)	≥ 98%
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.