Description

1-Methyl-2-Nitroimidazole is a versatile nitroimidazole derivative, a key heterocyclic building block in advanced organic synthesis. Its primary value lies in its role as a crucial intermediate for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of nitroimidazole-based antimicrobial and antiprotozoal agents. This high-purity compound is essential for research and production facilities in the pharmaceutical, agrochemical, and fine chemical industries, where precise chemical architecture is paramount for creating novel therapeutic and specialty compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nitroimidazole-class antibiotics and antiparasitic drugs, such as metronidazole analogs.
• Agrochemical Synthesis: Used in the research and development of novel fungicides and herbicides, leveraging its bioactive imidazole core.
• Fine Chemical Building Block: Serves as a versatile scaffold for constructing complex heterocyclic molecules in academic and industrial R&D.
• Material Science Research: Investigated for potential applications in the synthesis of specialized polymers and ligands for metal coordination.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	1-Methyl-2-Nitroimidazole
CAS No.	1671-82-5
Molecular Formula	C4H5N3O2
Molecular Weight	127.10 g/mol
Synonyms	2-Nitro-1-methylimidazole; 1-Methyl-2-nitro-1H-imidazole; 1-Methyl-2-nitroimidazole; NSC 51143; 1-Methyl-2-nitro-imidazole; 2-Nitro-1-methyl-1H-imidazole; 1H-Imidazole, 1-methyl-2-nitro-
EINECS	Contact for details

Quality Control

Our 1-Methyl-2-Nitroimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.