Description

tert-Butyldiphenylmethanol CAS NO 1657-60-9 is a versatile tertiary alcohol intermediate characterized by its sterically hindered structure, offering unique reactivity and stability. This compound is a critical building block in advanced organic synthesis, particularly valued for its role in constructing complex molecular architectures. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a precursor for ligands, protecting groups, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sterically hindered active pharmaceutical ingredients (APIs) and complex drug molecules.
• Ligand Synthesis: Used to prepare bulky phosphine and N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Agrochemical Production: Building block for creating advanced crop protection agents with enhanced stability and efficacy.
• Polymer Chemistry: Serves as a monomer or chain-transfer agent for producing specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed in Grignard reactions and as a nucleophile for constructing quaternary carbon centers.
• Material Science Research: Utilized in the development of novel organic electronic materials and liquid crystals.

Basic Information

Product Name	tert-Butyldiphenylmethanol
CAS No.	1657-60-9
Molecular Formula	C₁₇H₂₀O
Molecular Weight	240.34 g/mol
Synonyms	Diphenyl(tert-butyl)methanol; (1,1-Dimethylethyl)diphenylmethanol; t-Butyldiphenylcarbinol; α,α-Dimethylbenzhydrol; Benzhydrol, α,α-dimethyl-; 1,1-Dimethylethyl(diphenyl)methanol; NSC 404087; tert-Butyl(diphenyl)methanol
EINECS	Contact for details

Quality Control

Our tert-Butyldiphenylmethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including purity by HPLC/GC, identity confirmation by IR and NMR spectroscopy, and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.