Description

2-Bromophenyl Trifluoromethyl Sulphide 98 is a high-purity organosulfur compound featuring a brominated phenyl ring and a trifluoromethylthio group, making it a versatile building block in advanced chemical synthesis. Its unique structure provides a trifluoromethylthioether moiety, a valuable functional group for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds requiring the trifluoromethylthio (SCF3) group for enhanced bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromine atom allows for further functionalization.
• Material Science Research: Serves as a precursor for novel organic electronic materials and liquid crystals, leveraging the electronic properties of the sulfur and fluorine atoms.
• Cross-Coupling Reactions: The aryl bromide moiety makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings to create complex biaryl structures.
• Ligand and Catalyst Development: Employed in the design of specialized ligands for catalysis and molecular recognition applications.
• Fluorine Chemistry Studies: A valuable compound for investigating the introduction and behavior of fluorine-containing groups in organic molecules.

Basic Information

Product Name	2-Bromophenyl Trifluoromethyl Sulphide 98
CAS No.	1644-72-0
Molecular Formula	C7H4BrF3S
Molecular Weight	257.07 g/mol
Synonyms	1-Bromo-2-((trifluoromethyl)thio)benzene; 2-Bromo-α,α,α-trifluorothioanisole; (2-Bromophenyl)(trifluoromethyl) Sulfide; 2-Bromophenyl Trifluoromethyl Sulfide; 2-Bromobenzene Trifluoromethyl Thioether; o-Bromophenyl Trifluoromethyl Sulphide; S-Trifluoromethyl 2-bromobenzenethiol
EINECS	Contact for details

Quality Control

Our 2-Bromophenyl Trifluoromethyl Sulphide 98 is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure the specified purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.