Description

4-Isoxazolecarboxylic Acid, 5-(4-Fluorophenyl)-3-Methyl-, Ethyl is a high-value fluorinated heterocyclic building block with significant synthetic utility. This compound is prized for its role as a key intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole and fluorophenyl motifs.
• Material Science Research: Serves as a specialized monomer or building block for developing advanced polymers, liquid crystals, or organic electronic materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging agent in the design of chemical probes, enzyme substrates, or inhibitors for biological pathway studies.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university laboratories and contract research organizations (CROs).

Basic Information

Product Name	4-Isoxazolecarboxylic Acid, 5-(4-Fluorophenyl)-3-Methyl-, Ethyl
CAS No.	1644-03-7
Molecular Formula	C13H12FNO3
Molecular Weight	249.24 g/mol
Synonyms	Ethyl 5-(4-Fluorophenyl)-3-methylisoxazole-4-carboxylate; 5-(4-Fluorophenyl)-3-methyl-4-isoxazolecarboxylic Acid Ethyl Ester; 4-Carbethoxy-5-(4-fluorophenyl)-3-methylisoxazole; 3-Methyl-5-(p-fluorophenyl)isoxazole-4-carboxylic Acid Ethyl Ester; 1644-03-7; Ethyl 3-methyl-5-(4-fluorophenyl)-1,2-oxazole-4-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 4-Isoxazolecarboxylic Acid, 5-(4-Fluorophenyl)-3-Methyl-, Ethyl is produced and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to ensure identity and consistency. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.