Description

Diethylcarbamazine Citrate is the citrate salt of diethylcarbamazine, an important synthetic anthelmintic compound. It is a critical active pharmaceutical ingredient (API) valued for its potent anti-filarial properties. This compound is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of treatments for parasitic worm infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in anti-filarial medications for the treatment of lymphatic filariasis (elephantiasis) and river blindness (onchocerciasis).
• Veterinary Medicine: Formulation of anthelmintic treatments for parasitic infections in animals, including heartworm prevention and treatment in dogs.
• Biomedical Research: A key reference standard and tool compound in parasitology research for studying filarial nematode biology and screening new therapeutic agents.
• Clinical Trial Material: Sourcing of GMP-grade material for clinical studies and development of next-generation antiparasitic drug formulations.
• Bulk Pharmaceutical Manufacturing: Supply to contract manufacturing organizations (CMOs) and generic drug producers for large-scale production of finished dosage forms (e.g., tablets).

Basic Information

Product Name	Diethylcarbamazine Citrate
CAS No.	1642-54-2
Molecular Formula	C10H21N3O·C6H8O7
Molecular Weight	391.42 g/mol
Synonyms	Diethylcarbamazine Acid Citrate; 1-Diethylcarbamyl-4-methylpiperazine Citrate; Hetrazan; Banocide; Carbilazine; Notezine; Supatonin; N,N-Diethyl-4-methyl-1-piperazinecarboxamide Citrate (1:1)
EINECS	Contact for details

Quality Control

Our Diethylcarbamazine Citrate is manufactured under strict quality management systems. We offer material compliant with major pharmacopoeial standards, including USP and EP monographs. Every batch undergoes rigorous analytical testing to ensure identity, purity, and potency. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological quality is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%
Microbial Enumeration	Complies with EP/USP <61> requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.