Description

Suramin Sodium is a polysulfonated naphthylurea derivative with significant biological activity. This compound is valued for its potent and selective inhibitory properties against a range of parasitic and viral enzymes. It serves as a critical research tool and active pharmaceutical ingredient for the life sciences and pharmaceutical development sectors, particularly in studies of trypanosomiasis, oncology, and antiviral research.

Application

• Parasitology Research: A key investigative compound for studying African trypanosomiasis (sleeping sickness) and onchocerciasis (river blindness).
• Oncology Research: Used in preclinical studies to investigate its effects on tumor growth, angiogenesis, and purinergic signaling pathways.
• Antiviral Research: Employed as a research chemical to study the inhibition of reverse transcriptase and other viral replication mechanisms.
• Biochemical Tool: Acts as a selective antagonist for P2X and P2Y purinergic receptors in signal transduction research.
• Pharmaceutical Intermediates: Serves as a starting material or reference standard in the synthesis and quality control of related therapeutic agents.
• Enzyme Inhibition Studies: Utilized to study the function of various enzymes, including DNA polymerases, reverse transcriptases, and telomerase.

Basic Information

Product Name	Suramin Sodium
CAS No.	129-46-4
Molecular Formula	C51H34N6Na6O23S6
Molecular Weight	1429.21 g/mol
Synonyms	Suramin Hexasodium Salt; Antrypol; Bayer 205; Germanin; Fourneau 309; Naganol; Moranyl; 129-46-4; 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
EINECS	204-949-3

Quality Control

Our Suramin Sodium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 1.0%
pH (1% Solution)	6.0 - 8.0
Solubility	Freely soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.