Description

Hexamethylphosphorous Triamide (CAS NO 1608-26-0) is a versatile organophosphorus compound primarily valued as a powerful, non-nucleophilic base and a key reagent in organic synthesis. Its significance lies in its ability to facilitate challenging reactions, such as deprotonations and cyclizations, under mild conditions, often with high selectivity and yield. This makes it an essential material for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking efficient synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: Employed as a key reagent in the production of active pharmaceutical ingredients (APIs), particularly for deprotonation steps and the formation of complex heterocycles.
• Agrochemical Manufacturing: Used in the synthesis of advanced pesticides, herbicides, and plant growth regulators where its base properties are crucial for constructing specific molecular frameworks.
• Polymer Chemistry: Acts as a catalyst or co-catalyst in polymerization reactions and in the synthesis of specialized polymers and phosphatzene materials.
• Organic Synthesis Reagent: A valuable tool in research laboratories for a variety of transformations, including Wittig-type reactions, eliminations, and as a ligand for metal complexes.
• Chemical Vapor Deposition (CVD) Precursor: Serves as a phosphorus source in the CVD process for depositing thin films in semiconductor and electronics manufacturing.
• Ligand in Coordination Chemistry: Utilized to form complexes with transition metals, modifying their catalytic activity and selectivity for specific organic reactions.

Basic Information

Product Name	Hexamethylphosphorous Triamide
CAS No.	1608-26-0
Molecular Formula	C6H18N3P
Molecular Weight	163.20 g/mol
Synonyms	Hexamethylphosphorous Triamide; Tris(dimethylamino)phosphine; Phosphorous Tris(dimethylamide); HMPT; Tris(N,N-dimethylamino)phosphine; P(NMe2)3; Tris(dimethylamino)phosphorus; 1,1',1''-Phosphorous Triyltris(N-methylmethanamine)
EINECS	Contact for details

Quality Control

Our Hexamethylphosphorous Triamide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including assay by GC or NMR and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment to guarantee traceability and compliance with your internal quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its sensitivity to moisture and air, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.