Description

Bis(Dimethylamino)Phosphoryl Chloride is a versatile organophosphorus reagent primarily used as a key intermediate in the synthesis of complex molecules. Its high reactivity as a phosphorylating and chlorinating agent makes it invaluable for constructing phosphorus-nitrogen bonds under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients, ligands, and flame retardants.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of prodrugs, nucleotide analogs, and other bioactive molecules requiring phosphoramidate or phosphorodiamidate linkages.
• Agrochemical Synthesis: Used in the production of insecticides, herbicides, and plant growth regulators that contain phosphorus-based functional groups.
• Ligand & Catalyst Preparation: Serves as a precursor for phosphorus-nitrogen (P-N) ligands used in homogeneous catalysis and coordination chemistry.
• Flame Retardant Production: An intermediate in the manufacture of phosphorus-containing flame retardants for polymers and textiles.
• Polymer Modification: Employed to introduce phosphoramidate groups into polymer chains to alter material properties like adhesion or flame resistance.
• Chemical Research & Development: A valuable building block in organic and medicinal chemistry for constructing novel phosphorus heterocycles and functional materials.

Basic Information

Product Name	Bis(Dimethylamino)Phosphoryl Chloride
CAS No.	1605-65-8
Molecular Formula	C4H12ClN2OP
Molecular Weight	170.58 g/mol
Synonyms	Phosphorodichloridic Acid, Bis(dimethylamide); N,N,N',N'-Tetramethylphosphorodiamidic Chloride; Tetramethylphosphorodiamidic Chloride; Bis(dimethylamido)phosphoryl Chloride; Chloro-N,N,N',N'-tetramethylphosphonic Diamide; Phosphonic Diamide, N,N,N',N'-tetramethyl-, chloride; (Dimethylamino)phosphoryl Dichloride, Bis-; DMAP-Cl
EINECS	Contact for details

Quality Control

Our Bis(Dimethylamino)Phosphoryl Chloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.