Description

Ethyl-2,2,2-D3-Triphenylphosphonium Bromide is a deuterium-labeled quaternary phosphonium salt, a crucial isotopically labeled reagent for advanced organic synthesis and mechanistic studies. Its primary value lies in enabling precise isotopic tracing in Wittig and related ylide reactions, allowing researchers to track reaction pathways and kinetics with high specificity. This compound is essential for pharmaceutical R&D, agrochemical development, and academic research focused on reaction mechanisms, where deuterium labeling is required for mass spectrometry analysis or to study kinetic isotope effects.

Application

• Deuterium-Labeled Wittig Reagent: Serves as a key precursor for generating deuterium-labeled ylides to synthesize alkenes with specific deuterium incorporation.
• Mechanistic Studies & Kinetic Isotope Effect (KIE) Analysis: Used as a probe in organic reaction mechanisms to investigate the role of specific hydrogen atoms via deuterium substitution.
• Pharmaceutical Intermediate Synthesis: Enables the preparation of deuterated drug candidates and active pharmaceutical ingredients (APIs) for metabolic stability and bioavailability studies.
• Mass Spectrometry & Analytical Standards: Acts as an internal standard or a labeled building block for creating compounds used in quantitative LC-MS and GC-MS analysis.
• Agrochemical Research: Applied in the synthesis of deuterium-labeled pesticides or herbicides to study environmental fate, degradation, and metabolic pathways.
• Material Science Research: Used in the synthesis of specialty polymers or organic electronic materials where deuterium labeling is needed to study structure-property relationships.

Basic Information

Product Name	Ethyl-2,2,2-D3-Triphenylphosphonium Bromide
CAS No.	1560-55-0
Molecular Formula	C20H17D3P·Br
Molecular Weight	Contact for details
Synonyms	Ethyl-2,2,2-d3-triphenylphosphonium bromide; (2,2,2-Trideuterioethyl)triphenylphosphonium bromide; Deuterated Ethyltriphenylphosphonium Bromide; (CD3CH2)PPh3Br; Ethyl-d3 Triphenylphosphonium Bromide; Triphenyl(2,2,2-trideuterioethyl)phosphonium Bromide; ETPB-d3
EINECS	Contact for details

Quality Control

Our Ethyl-2,2,2-D3-Triphenylphosphonium Bromide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ³¹P) and HPLC to confirm chemical structure, isotopic purity (D-enrichment), and chemical purity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on assay, deuterium content, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Deuterium Content (NMR/MS)	≥ 98 atom % D
Assay (HPLC/NMR)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.