Description

Piperidine-1-Ylphosphonic Aciddichloride is a specialized organophosphorus compound, serving as a key reactive intermediate in advanced chemical synthesis. Its value lies in its ability to introduce the piperidinylphosphonic acid moiety, a crucial building block for creating complex molecules with tailored properties. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of novel drug candidates, particularly those targeting neurological disorders and as potential enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and plant growth regulators that require specific phosphonate functionalities.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized phosphine-based ligands used in homogeneous catalysis and metal complexation.
• Material Science Research: Employed in the development of flame retardants, corrosion inhibitors, and specialty polymers where phosphorus incorporation enhances material performance.
• Peptide Mimetics and Bioconjugation: Useful in medicinal chemistry for creating phosphate isosteres and developing bioconjugation linkers for targeted drug delivery systems.
• Chemical Biology Probes: Acts as a key reagent for synthesizing activity-based probes to study enzyme function and mechanism.

Basic Information

Product Name	Piperidine-1-Ylphosphonic Aciddichloride
CAS No.	1498-56-2
Molecular Formula	C5H10Cl2NO2P
Molecular Weight	210.02 g/mol
Synonyms	Piperidinophosphonic Dichloride; 1-Piperidinophosphonic Dichloride; Phosphorodichloridic Acid, 1-Piperidinol Ester; N-(Dichlorophosphinyl)piperidine; Piperidine, 1-(dichlorophosphinyl)-; Piperidin-1-ylphosphonic Dichloride; Piperidino Phosphorodichloridate
EINECS	Contact for details

Quality Control

Every batch of Piperidine-1-Ylphosphonic Aciddichloride undergoes rigorous analytical testing to ensure it meets the high standards required for sensitive synthetic applications. Our quality assurance protocol includes identity confirmation, purity assessment, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.