Description

2-Fluoro-5-Methylthiophene is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique fluorine-substituted thiophene core imparts desirable electronic and metabolic properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or building block for conjugated polymers and organic semiconductors used in OLEDs, organic photovoltaics, and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and in the synthesis of metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on heterocyclic systems in academic and industrial R&D settings.

Basic Information

Product Name	2-Fluoro-5-Methylthiophene
CAS No.	1481-00-1
Molecular Formula	C5H5FS
Molecular Weight	116.16 g/mol
Synonyms	5-Methyl-2-fluorothiophene; 2-Fluoro-5-methylthiophene; 5-Methyl-2-fluorothiophene; 2-Fluor-5-methylthiophen; Thiophene, 2-fluoro-5-methyl-; 2-Fluoro-5-methyl-thiophene; 2-Fluor-5-methyl-thiophen
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylthiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.