Description

1-Methylpsilocin is a synthetic tryptamine derivative of significant interest in pharmacological and neuroscience research. This compound is valued for its role as a reference standard and a key intermediate in the study of serotonin receptor activity and neurochemical pathways. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and analytical service providers engaged in neuropharmacology, medicinal chemistry, and forensic analysis.

Application

• Pharmacological Research: Used as a reference standard in studies investigating serotonin (5-HT) receptor subtypes, particularly the 5-HT2A receptor.
• Medicinal Chemistry: Serves as a crucial intermediate or analog in the synthesis and structure-activity relationship (SAR) studies of novel psychoactive substances and potential therapeutics.
• Neuroscience Studies: Employed in *in vitro* and *in vivo* models to understand neurotransmitter systems, hallucinogenic mechanisms, and cognitive processes.
• Analytical Reference Standard: Essential for the calibration of analytical equipment (HPLC, GC-MS, LC-MS) in forensic, toxicology, and quality control laboratories for accurate compound identification and quantification.
• Biochemical Assay Development: Used in the development and validation of high-throughput screening assays for receptor binding and functional activity.

Basic Information

Product Name	1-Methylpsilocin
CAS No.	1465-16-3
Molecular Formula	C13H18N2O
Molecular Weight	218.30 g/mol
Synonyms	4-Hydroxy-N,N,N-trimethyltryptamine; 3-[2-(Dimethylamino)ethyl]-1-methyl-1H-indol-4-ol; 4-HO-MET; Metocin; 1-Methyl-4-hydroxy-N,N-diethyltryptamine (common misnomer); 1-Methylpsilocybin metabolite; 1-MeO-4-HO-DMT (analogous naming)
EINECS	Contact for details

Quality Control

Our 1-Methylpsilocin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination, IR and NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). For long-term storage, consider keeping the material under inert atmosphere at lower temperatures (-20°C) to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (¹H NMR, ¹³C NMR)
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.