Description

Phenylmethanethiosulfonate is a specialized organosulfur compound with the CAS number 1197-26-8, serving as a valuable reagent in synthetic organic chemistry. Its core value lies in its role as a versatile building block and protecting group, particularly for thiol functionalities in complex molecule synthesis. This chemical is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of drug candidates, particularly those containing sulfur-based pharmacophores.
• Peptide Chemistry: Used as a protective group for cysteine residues during solid-phase peptide synthesis (SPPS).
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Precursor in the development of functionalized polymers and organic electronic materials.
• Chemical Biology Research: Tool compound for studying protein thiol modifications and redox signaling pathways.
• Cross-coupling Reactions: Serves as an electrophilic sulfur source in transition metal-catalyzed reactions.

Basic Information

Product Name	Phenylmethanethiosulfonate
CAS No.	1197-26-8
Molecular Formula	C7H8O2S2
Molecular Weight	188.27 g/mol
Synonyms	Benzylthiosulfonate; S-(Phenylmethyl) thiosulfonate; Benzyl thiosulfonate; Thioperoxybenzoic acid S-benzyl ester; Phenylmethyl thiosulfonate; BTS; Benzylsulfonothioate
EINECS	214-822-9

Quality Control

Our Phenylmethanethiosulfonate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request, supporting compliance with internal quality standards and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.