Description

4,5-Dimethyl-1H-Imidazole-2-Thiol is a versatile sulfur-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, acting as both a nucleophile and a ligand, which makes it indispensable for creating complex molecular architectures. This high-purity intermediate is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical producers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of histamine H3 receptor antagonists, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Building block for developing novel fungicides, herbicides, and plant growth regulators.
• Coordination Chemistry & Catalysis: Acts as a versatile ligand for transition metals, useful in creating catalysts for cross-coupling and other organic transformations.
• Polymer Additive: Used as a stabilizer or curing agent in the production of specialty polymers and resins.
• Chemical Research & Development: Fundamental reagent in heterocyclic chemistry for constructing imidazole-based libraries and novel compounds.
• Material Science: Intermediate in the development of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	4,5-Dimethyl-1H-Imidazole-2-Thiol
CAS No.	1192-72-9
Molecular Formula	C5H8N2S
Molecular Weight	128.19 g/mol
Synonyms	2-Mercapto-4,5-dimethylimidazole; 4,5-Dimethyl-2-mercaptoimidazole; 4,5-Dimethyl-2-imidazolethiol; NSC 403697; 2-Thiol-4,5-dimethylimidazole; 4,5-Dimethyl-1H-imidazole-2-thione (tautomer); 4,5-Dimethylimidazole-2-thiol
EINECS	214-759-8

Quality Control

Our production of 4,5-Dimethyl-1H-Imidazole-2-Thiol adheres to stringent quality management protocols. Every batch is characterized and tested to ensure high chemical purity and consistency, meeting the exacting standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.