Description

n-[2-(Acetylthio)Ethyl]Phthalimide is a specialized organosulfur compound featuring a phthalimide core linked to an acetylthioethyl moiety, serving as a key synthetic intermediate. This compound is valued for its role in introducing protected thiol functionalities into target molecules, enabling precise chemical modifications. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of drug candidates, particularly those requiring thioether or disulfide linkages.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the thiol group is essential for biological activity.
• Bioconjugation Chemistry: Serves as a reagent for modifying proteins, peptides, or other biomolecules via thiol-reactive chemistry.
• Polymer Modification: Employed to introduce functional thiol groups into polymer chains for cross-linking or creating responsive materials.
• Chemical Research: A versatile reagent in organic synthesis for constructing complex sulfur-containing heterocycles and molecules.
• Material Science: Used in the development of self-assembled monolayers (SAMs) and surface functionalization on gold or other metals.

Basic Information

Product Name	n-[2-(Acetylthio)Ethyl]Phthalimide
CAS No.	1084-55-5
Molecular Formula	C₁₂H₁₁NO₃S
Molecular Weight	249.28 g/mol
Synonyms	N-(2-Acetylthioethyl)phthalimide; 2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] ethanethioate; 2-(2-Phthalimidoethylthio)acetate; S-Acetyl-2-mercaptoethylphthalimide; N-(2-Mercaptoethyl)phthalimide S-acetate; Acetylthioethylphthalimide; ATEP
EINECS	214-122-7

Quality Control

Our n-[2-(Acetylthio)Ethyl]Phthalimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	97 - 102 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.