Description

Cyclopropyl(1H-Indol-6-Ylmethyl)Amine CAS NO 1079-86-3 is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-cyclopropylamine hybrid structure. This compound is of significant commercial importance as a critical building block in the synthesis of novel bioactive molecules, particularly in central nervous system (CNS) and oncology research. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs), especially those targeting serotonin and dopamine receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Biochemical Tool Compound: Employed in pharmacological assays to study receptor-ligand interactions and enzyme inhibition related to neurological pathways.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex heterocyclic compounds with potential biological activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	Cyclopropyl(1H-Indol-6-Ylmethyl)Amine
CAS No.	1079-86-3
Molecular Formula	C13H16N2
Molecular Weight	200.28 g/mol
Synonyms	6-[(Cyclopropylamino)methyl]-1H-indole; 1H-Indole-6-methanamine, N-cyclopropyl-; N-Cyclopropyl-1H-indole-6-methanamine; Cyclopropyl(1H-indol-6-ylmethyl)amine; (6-Indolylmethyl)cyclopropylamine; CPIMA; Cyclopropylamino-methylindole
EINECS	Contact for details

Quality Control

Our Cyclopropyl(1H-Indol-6-Ylmethyl)Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and relevant ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.