Description

5-Chloro-2-Methylindole is a versatile halogenated indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure makes it an essential intermediate for the development of pharmaceuticals, agrochemicals, and functional materials. This high-purity compound is primarily sought by research institutions and industrial manufacturers engaged in the synthesis of complex bioactive molecules and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic semiconductors, dyes, and photostable polymers.
• Biochemical Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for library development in high-throughput screening.
• Fine Chemical Production: Integral in multi-step syntheses for producing complex, high-value specialty chemicals and advanced intermediates.

Basic Information

Product Name	5-Chloro-2-Methylindole
CAS No.	1075-35-0
Molecular Formula	C9H8ClN
Molecular Weight	165.62 g/mol
Synonyms	2-Methyl-5-chloroindole; 5-Chloro-2-methyl-1H-indole; 1H-Indole, 5-chloro-2-methyl-; 5-Chloro-2-methylindole; 2-Methyl-5-chloro-1H-indole; 5-Chloro-2-methylindol; 5-Chloro-2-methyl-1H-indole
EINECS	214-064-6

Quality Control

Our 5-Chloro-2-Methylindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing purity, identity, and impurity profiles as verified by advanced analytical techniques. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.