Description

Ethyl 5-Fluoro-1H-Indazole-3-Carboxylate is a high-purity fluorinated indazole derivative, serving as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its core value lies in enabling the development of novel bioactive molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and manufacturers in pharmaceutical R&D, agrochemical discovery, and advanced material science who require a reliable, high-quality source for complex heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to the bioactivity of the fluorinated indazole scaffold.
• Chemical Biology & Medicinal Chemistry: Serves as a crucial scaffold for constructing compound libraries in drug discovery and hit-to-lead optimization programs.
• Material Science Precursor: Potential use in the synthesis of specialized organic ligands and functional materials.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies and the development of new synthetic routes for complex heterocycles.

Basic Information

Product Name	Ethyl 5-Fluoro-1H-Indazole-3-Carboxylate
CAS No.	1016-36-0
Molecular Formula	C10H9FN2O2
Molecular Weight	208.19 g/mol
Synonyms	5-Fluoro-1H-indazole-3-carboxylic acid ethyl ester; Ethyl 5-fluoroindazole-3-carboxylate; 3-Carbethoxy-5-fluoroindazole; 5-Fluoroindazole-3-carboxylic Acid Ethyl Ester; 1H-Indazole-3-carboxylic acid, 5-fluoro-, ethyl ester; 1016-36-0; Ethyl 5-fluoro-1H-indazole-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Fluoro-1H-Indazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.